Winona, MO

ZIP code 65588 centers on Winona in Shannon County, in Missouri’s Ozark highlands. Its landscape includes wooded hills, springs, and river corridors, with public lands forming a major local feature. Notable natural landmarks in the area include Greer Spring, the Eleven Point National Scenic River, and Mark Twain National Forest. Winona sits along U.S. Route 60, serving as a small service center for nearby rural communities and outdoor recreation.