Newtonia, MO

The 64853 ZIP code serves Seneca, a small community in Newton County in southwestern Missouri, near the Oklahoma border. The town lies along the Spring River and old U.S. Route 66. Its best-known historic landmark is the Route 66 bridge over the river, a concrete arch bridge dating to the early 1920s. Seneca’s downtown is the area’s main center for local businesses and civic services.