Defiance, MO

ZIP code 63341 covers Defiance and surrounding rural areas in St. Charles County, Missouri, west of St. Louis. Its best-known historic landmark is the Daniel Boone Home and Heritage Center, a preserved early-19th-century residence and living-history complex. Katy Trail State Park also passes through Defiance, offering access to its rail-trail route amid wooded bluffs, farmland, and nearby wine-country scenery.